Active Clinical Trials

Help our researchers make discoveries in nutrition and wellness science by participating in a clinical trial.

Clinical trials offer our researchers the opportunity to study the effects of nutrition and behavioral interventions on real people. Participation in a clinical trial helps our scientists move their research forward, and it may also have positive effects on your own health and wellness journey. Eligibility for clinical trials depends on many factors; if you're interested in participating, please read the individual trial information to determine whether you are eligible for the study.

Exercise and Donor Immune Cell Xenotransplantation

Healthy, non-smoking individuals between the ages of 21-44 are needed to participate in a study investigating the relationship between exercise and the immune cell numbers within the blood.

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Exercise and Total Viral Immunity

Healthy, non-smoking individuals between the ages of 18-44 are needed to participate in a study investigating the effectiveness of exercise to beneficially alter immunity against SARS-CoV-2 and many other common respiratory viruses.

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Grape Powder Study

Healthy, non-smoking men and women are needed for a research study examining the effects of a freeze-dried grape powder on markers of metabolic and vascular health, including blood pressure and cholesterol.

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Hot Yoga Study

We are looking for healthy females with no yoga experience to participate in a study that will examine the body's ability to adapt to heat and exercise by participating in hot yoga.

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Salivary Gland Wound Healing After Radiotherapy

This is a research study investigating radiation treatment-induced salivary gland damage; participants are referred by their clinicians.

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EXERCISE AND DONOR IMMUNE CELL XENOTRANSPLANTATION


We are recruiting healthy, non-smoking individuals between the ages of 21-44 to participate in a study investigating the relationship between exercise and the immune system. This study aims to understand how exercise changes immune cell numbers within the blood and whether or not these changes can positively impact outcomes if used in a cancer transplant setting. Participants must not have cardiovascular disease, asthma, or be taking medications that affect immune function (i.e. ibuprofen/aspirin, anti-histamines).

The first part of this study will require participants to complete cycling exercise trials on two separate occasions. The second part of this study involves five additional exercise bouts where participants will be given either a placebo or a beta blocker drug. The total time commitment for part one is ~4 hours; the total time commitment for part two is ~20 hours. Upon completion of the study, participants will receive compensation of $50 if they complete part one and $150 if they complete part two.

If interested, please email Dr. Richard Simpson at rjsimpson@arizona.edu.

This study is being conducted by Dr. Richard Simpson, School of Nutritional Sciences and Wellness at the University of Arizona and has been approved by the Institutional Review Board (IRB) of the University of Arizona.

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EXERCISE AND TOTAL VIRAL IMMUNITY


We are recruiting healthy, non-smoking individuals between the ages of 18-44 to participate in a study investigating the relationship between exercise and the immune system. This study aims to assess the effectiveness of exercise to beneficially alter immunity against SARS-CoV-2 and many other common respiratory viruses. Participants must not have cardiovascular disease, asthma, or be taking medications that affect immune function (i.e. ibuprofen/aspirin, anti-histamines).

Participants will be required to engage in three to five exercise sessions and provide blood samples. The total time commitment will be between 4-12 hours, and participants will receive compensation up to $150; total time commitment and compensation are dependent upon the number of exercise trials completed.

If interested, please email Dr. Richard Simpson at rjsimpson@arizona.edu.

This study is being conducted by Dr. Richard Simpson, School of Nutritional Sciences and Wellness at the University of Arizona and has been approved by the Institutional Review Board (IRB) of the University of Arizona.

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GRAPE POWDER STUDY


We are seeking participants 30 - 65 years of age with a BMI of 25-36 kg/m2. Participants must be healthy and not taking medications for high cholesterol, blood pressure, diabetes, or inflammatory conditions.

Participants will be provided with freeze-dried grape powder and a placebo powder for 6 - 8 weeks each, with a 4-week break between test periods (total time for study is 16-20 weeks).  At the completion of the study, participants will receive lab results and compensation of $350.

If you are interested in learning more about the study, please call 520-621-5382 or email FBHlab@email.arizona.edu, mention the Grape Study, and leave your name and a contact number.

This study is being conducted by Dr. Ann Skulas-Ray, School of Nutritional Sciences and Wellness at the University of Arizona and has been approved by the Institutional Review Board (IRB) of the University of Arizona.

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HOT YOGA STUDY


We are looking for healthy females with no yoga experience to participate in a study that will examine the body's ability to adapt to heat and exercise by participating in hot yoga.

There is no cost to participate - all yoga classes are included. Participants will receive a Fitbit Inspire 3 for use during the study and will be able to keep it after the study conclusion.

For more information and/or questions regarding the study, contact Maria Luz Fernandez (520-621-6606 | mlfernandez@arizona.edu).

An Institutional Review Board (IRB) responsible for human subjects research at the University of Arizona reviewed this research project and found it to be acceptable, according to applicable state and federal regulations and University policies designed to protect the rights and welfare of participants in research.

FREQUENTLY ASKED QUESTIONS

Hot Yoga is performing a sequence of yoga poses in a heated room. The temperature of the room will be approximately 104°F. For this study, Hot Yoga sessions will last 60 minutes.

We are recruiting healthy women 30-50 years of age. For more participation criteria, see below.

This is a 14-week study. The yoga intervention will last 6 weeks.

This is a yoga intervention study.

You will be required to participate in hot yoga 3x per week for 6 weeks, provide blood samples 9 times throughout the study, and fill out questionnaires that assess mental health, emotional stress, and anxiety after yoga.

It costs nothing to participate in this study.

Participants will be provided with access to Hot Yoga classes for the duration of the study and will be provided with a Fitbit Inspire 3 fitness tracker ($100 value) that will be used during the study and will be theirs to keep after the study is completed.

No previous yoga experience is necessary to participate in this study. See inclusion criteria below.

The inclusion criteria are as follows:

  • Healthy women between the ages of 30 and 50, not post-menopausal
  • Not pregnant and not planning to get pregnant during the study duration
  • Not lactating
  • Have not used tobacco products (i.e. cigarettes, e-cigs, vaping) in the last 6 months
  • Have not participated in yoga or hot yoga in the last 12 months
  • Able to give informed consent and be willing to participate for the entirety of the study
  • Agree to allow samples to be stored for future use
  • Pass the preliminary study screening
  • Answer no for every question on the Physical Activity Readiness Questionnaire (PAR-Q) during preliminary screening
  • Not taking any of the following drugs:
    • Taking greater than 100 mg aspirin / day
    • Daily NSAIDS (aspirin, acetaminophen (Tylenol), ibuprofen (Advil/Motrin), or oral corticosteroids
    • Monteleukast-type of allergy medications (i.e. Singulair)
    • Cholesterol lowering medications (i.e. statins, niacin, etc.)
  • Not have any of the following health conditions:
    • Fasting glucose greater than 125 mg/dl
    • Fasting triglycerides greater than 150 mg/dl
    • Blood pressure greater than 130/90
    • BMI equal to or greater than 30 or less than 19
    • A pacemaker or a defibrillator

Yes, you can withdraw from the study at any time for any reason.

For more information regarding the Hot Yoga study please contact:

UA Hot Yoga Study Research Team
mlfernandez@arizona.edu
520-621-6606


SALIVARY GLAND WOUND HEALING AFTER RADIOTHERAPHY


This is a research study investigating radiation treatment-induced salivary gland damage. Eligibility includes adults undergoing standard of care surgery for cancer in the head and neck region. Salivary gland tissue that is being removed as part of the standard surgical treatment, and which would otherwise be discarded, will be collected and studied in the laboratory.

The purpose of this research study is to understand how radiation treatment causes damage to salivary glands and to learn how we might prevent such damage. No foreseeable risks or discomfort is anticipated from the research, since the tissue will be collected after it is removed as part of a normally scheduled surgery.

If interested, please email Dr. Kirsten Limesand at limesank@arizona.edu.

This study is being conducted by Dr. Kirsten Limesand, School of Nutritional Sciences and Wellness at the University of Arizona and has been approved by the Institutional Review Board (IRB) of the University of Arizona.

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